n-sulfonylketenimines as useful synthons in a novel synthesis of functionalized 2-oxoindoline derivatives

Authors

issa yavari

manijeh nematpour

esmat sodagar

abstract

the synthesis of a novel class of 2-oxoindolin-3-ylidene-(1-arylhydrazinyl)-2-aryl(alkyl)ethylidene derivativesvia a copper-catalyzed tandem reaction of isatin, arylhydrazines, sulfonyl azides and terminal alkynes is described.

Sign up for free to access the full text

Already have an account?login

similar resources

N-Sulfonylketenimines as Useful Synthons in a Novel Synthesis of Functionalized 2-Oxoindoline Derivatives

The synthesis of a novel class of 2-oxoindolin-3-ylidene-(1-arylhydrazinyl)-2-aryl(alkyl)ethylidene derivativesvia a copper-catalyzed tandem reaction of isatin, arylhydrazines, sulfonyl azides and terminal alkynes is described.

full text

part a: application of n-(p-toluenesulfonyl) imidazole (tsim) and triphenylphosphine/carbon tetrachloride in several organic transformations part b: application of 8-bromocaffeine for synthesis of some novel 8-caffeinyl derivatives

بخش اول این پایان نامه به طور عمده بر توسعه کاربردهای جدید n-(پارا-تولوئن سولفونیل) ایمیدازول (tsim) و تری فنیل فسفین/ تتراکلرید کربن در تبدیل گروههای عاملی به یکدیگر استوار است. نظر به تنوع زیاد، دردسترس بودن، سمیت کمتر و نقل و انتقال آسان تر الکل ها نسبت به آلکیل هالیدها، تبدیل مستقیم گروه هیدروکسیل به گروه های عاملی دیگر مثل آزید، نیتریل و استر یکی از مهم ترین تبدیلات در سنتزهای آلی است. با ...

15 صفحه اول

Green Chemical Synthesis and Biological Evaluation of Novel N-substituted Rhodanine Derivatives as Potential Antifungal Agents

Background and purpose: In medicinal chemistry, molecules containing rhodanine(2-thiazolidine-4-one) ring as a magic multifunctional privileged structural and functional scaffold show a broad range of potent pharmacological properties containing anti-microbial, antiviral, anti-diabetic, and anti-convulsant effects. Evidence suggests that the activity of the rhodanine derivative correlates with ...

full text

Application of Nicotinic Acid Functionalized Chlorosulfonic Acid as a Green Catalyst for the Synthesis of Bis(2-methyl-1Hindole)Derivatives

3-Carboxy-1-sulfopyridin-1-ium chloride ([CPySO3H]+Cl-) as a novel ionic organocatalyst for thecondensation of aldehydes and 2-methylindole to synthesize bis(2-methyl-1H-indole) derivatives inacetonitrile at room temperature has been developed. Some tetrakis (2-methyl-1H-indole)derivatives have also been synthesized by the reaction of 2,2'-(butane-1,4-diylbis(oxy))dibenzaldehyde and 2-methylind...

full text

2-(4-Fluorophenyl)-N-phenylacetamide Derivatives as Anticancer Agents: Synthesis and In-vitro Cytotoxicity Evaluation

Cancer is a major global problem and is the second leading cause of mortality in the developed countries.Resistance to current chemotherapeutics and high incidence of adverse effects are the two principal reasons for developing new anticancer agents. Phenylacetamide derivatives can act as potential anticancer agents. Synthesis and screening of 2-(4-Fluorophenyl)-N-phenylacetamide derivatives in...

full text

2-(4-Fluorophenyl)-N-phenylacetamide Derivatives as Anticancer Agents: Synthesis and In-vitro Cytotoxicity Evaluation

Cancer is a major global problem and is the second leading cause of mortality in the developed countries.Resistance to current chemotherapeutics and high incidence of adverse effects are the two principal reasons for developing new anticancer agents. Phenylacetamide derivatives can act as potential anticancer agents. Synthesis and screening of 2-(4-Fluorophenyl)-N-phenylacetamide derivatives in...

full text

My Resources

Save resource for easier access later


Journal title:
organic chemistry research

Publisher: iranian chemical society

ISSN

volume 1

issue 1 2015

Keywords
[ 2 , ' o x o i n d o l i n e s ' , ' k e t e n i m i n e s ' , ' s u l f o n y l a z i d e ' , ' t e r m i n a l a l k y n e ' , ' i s a t i n ' ]

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023